Recent Findings

The research blog features scientific contributions made by study investigators and research collaborators highlighting findings from the PORCH and CHAP studies starting from 2019.

Temporal changes in the likelihood of dementia and MCI over 18 years in a population sample
Estimates dementia likelihood score and examines the change in this score between 1993 and 2012

Healthy lifestyle and the risk of Alzheimer’s dementia: Findings from two longitudinal studies
Quantifies the impact of smoking, alcohol consumption, physical activity, and diet on the disease risk

Race, APOE ε4, and Long-Term Cognitive Trajectories in a Biracial Population Sample
Examines the racial differences in the association of APOE e4 allele with Alzheimer’s disease and cognitive decline

Apolipoprotein E genotypes, age, race, and cognitive decline in a population sample
Provides the racial differences in the association of APOE genotypes with cognitive decline

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Identifies the associations of vascular risk factors and their genetic risk score with MRI-based brain infarcts

Prevalence and incidence of clinically diagnosed Alzheimer’s disease dementia from 1994 to 2012
Examines the time trend in prevalence and incidence of Alzheimer’s dementia between 1994 and 2012